Nursing research summary

Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II

Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II is a nursing research record that should be interpreted using the available source metadata.

ClinicalTrials.gov Published 2026 7 min read

In brief

Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II is a nursing research record that should be interpreted using the available source metadata.

What this article is about

Quick Answer

Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II is a nursing research record that should be interpreted using the available source metadata.

Student takeaways

Key Takeaways

  • The Mind Space application aims to enhance nonjudgmental awareness of thoughts, emotions, feelings, and behaviors among Thai university students
  • The intervention incorporates mindfulness practices (body scan, sitting meditation, mindful movement) delivered via an online application
  • Participants are guided to develop cognitive awareness and adaptive responses to stressors, focusing on managing automatic, negative, or irrational thoughts
  • The program aims for participants to cultivate more rational, flexible, and positive thinking patterns
  • Effectiveness will be assessed through short-term (8 weeks post-intervention) and long-term (6-month follow-up) outcomes compared to a control group

Student summary

Why This Research Matters

This article describes a clinical trial, titled 'Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II,' which aims to develop and test an online mindfulness application designed specifically for university students in Thailand. The study is being conducted by researchers from Mae Fah Luang University.

The research focuses on creating a digital tool called 'Mind Space' that teaches mindfulness techniques based on established programs like Mindfulness-Based Stress Reduction (MBSR) and Mindfulness-Based Cognitive Therapy (MBCT). These methods help people pay attention to their thoughts, feelings, and actions in the present moment without judging them. The goal is for students using this app to better understand how these internal experiences affect their mental health.

The study has two main parts: Phase I, which ran from October 2025 to September 2026, was about developing the application itself and checking if it could work well in a small test group. They also did a quick look at whether it might help with stress, anxiety, or depression. Phase II, planned for October 2026 to December 2026, is where they will really start using this app more widely.

The researchers plan to run the program in three universities located in Northern Thailand: Mae Fah Luang University, Phayao University, and Utraradit University. They are looking for volunteer students who meet certain conditions. To join Phase I (the pilot study), students must be enrolled in undergraduate programs at these specific universities during the Fall semester of 2026. Other requirements include being able to read, speak, and write Thai; having a score above 6 on the General Health Questionnaire (GHQ-28) which suggests they might have some mental health concerns; not having learning disorders like ADHD or other specific learning issues; no history of psychiatric problems such as schizophrenia, adjustment disorders, delusion disorders, or substance use disorders; and importantly, not having practiced meditation in the past six months. Students who are excluded include those with limitations for mindful movement (like hearing loss, blindness, or physical restrictions), or anyone who might feel too uncomfortable or distressed to participate fully in each session.

The core idea behind Mind Space is that by practicing mindfulness—through exercises like body scans, sitting meditation, and mindful movements via the app—students can learn to manage their wandering minds, negative thoughts, and irrational ideas. The hope is that this will lead them to think more flexibly and positively over time.

To see if the app works, they will measure its effects in both short-term (immediately after an 8-week program) and long-term (6 months later). They plan to compare a group of students who use Mind Space with a control group that does not. The main things they are looking at are changes in stress levels, anxiety, depressive symptoms, and overall mindfulness skills among the participants.

For nursing students reading this, it's important to understand how this research fits into broader efforts to support student mental health using technology-based interventions. You should critically appraise the study design (it is a clinical trial), the specific population being studied (Thai university undergraduates with some pre-existing mental health risk factors), and the chosen outcome measures (stress, anxiety, depression scales). The abstract does not provide information on sample sizes for Phase I or II, nor does it detail any preliminary findings from the pilot study mentioned in Phase I. It also doesn't specify whether this is a randomized controlled trial design for Phase II.

When considering how to reason from this evidence as a future nurse, you might think about how online mindfulness tools could be integrated into university health services or student support programs. You should consider the potential benefits of such interventions in reducing mental health burdens among students and the challenges related to implementation, accessibility (e.g., internet access), cultural adaptation (the app is for Thai students), and ensuring that these digital solutions are evidence-based and effective.

Regarding source and rights cautions: This information comes from ClinicalTrials.gov, a public registry. The record indicates it's 'source-linked' with an authority level of 'High.' While the platform provides access to trial metadata, full details or results may not be publicly available until after the study is completed and published elsewhere. Always check for official publications in peer-reviewed journals if you need detailed findings.

In summary, this clinical trial outlines a structured approach to developing and evaluating an online mindfulness application tailored for Thai university students. It addresses a relevant public health concern (student mental well-being) by leveraging technology and established psychological principles. The study design is methodical, with clear objectives for both development/testing phases and specific inclusion/exclusion criteria.

The abstract clearly states the primary aim of Phase II: 'To examine the effects of mindfulness-base intervention (Mindspace Application) on mental health outcomes for Thai university students.' It also mentions that investigators will develop the application based on MBSR and MBCT principles, encouraging participants to pay attention to their present thoughts, emotions, feelings, and behaviors without judgment. This non-judgmental awareness is intended to help them learn about the relationship between these internal states and their mental health outcomes (mindfulness, stress, anxiety, and depression). The intervention includes mindfulness practices like body scan, sitting meditation, and mindful movement using an online application, along with teaching participants how to shape thoughts and manage wandering minds. Ultimately, it aims for participants to become more flexible and positive thinkers.

The study's settings are three universities in Northern Thailand: Mae Fah Luang University, Phayao University, and Utraradit University. The population is Thai university students between years 1 and 4 (undergraduate). For Phase I recruitment during the Fall semester of 2026 at these specific universities, inclusion criteria were being an undergraduate student in years 1-4; able to read, speak, and write in Thai; scoring higher than 6 on the General Health Questionnaire (GHQ-28) indicating a risk for mental health problems; no history of learning disorders or psychiatric disorders (schizophrenia, adjustment disorders, delusion disorders, substance use disorders); and having no meditation experience within the past 6 months. Exclusion criteria were limitations for mindful movement (hearing loss, blindness, movement limitations) and being uncomfortable or distressed to participate in each session.

The conceptual framework is based on MBSR (Kabat-Zinn, 2003) and MBCT (Segal et al., 2002). The program aims to cultivate nonjudgmental awareness of thoughts, feelings, emotions, and behaviors among university students. It also aims to enhance participants' understanding of the interrelationships among cognitions, emotions, affective experiences, and behaviors that contribute to psychological distress like stress, anxiety, and depressive symptoms.

The intervention incorporates core mindfulness practices delivered via an online application: body scan exercises, sitting meditation, and mindfulness-based movement for relaxation. Participants will be guided to develop cognitive awareness and adaptive responses to internal and external stressors, with emphasis on recognizing and managing automatic thoughts (wandering mind), negative thoughts, and irrational or maladaptive cognitions. Through this process, participants are encouraged to cultivate more rational, flexible, and positive thinking patterns.

The researchers anticipate that the program will enhance mindfulness skills and contribute to reductions in stress, anxiety, and depressive symptoms among study participants. The effectiveness of Mind Space will be examined across short-term (baseline and immediately post-intervention at 8 weeks) and long-term periods (6-month follow-up). Outcomes in the intervention group will be compared with those in a control group. Primary outcome variables include mental health indicators—stress, anxiety, depressive symptoms—and levels of mindfulness among Thai university students. Data analysis will use one-way repeated-measures multivariate analysis of variance (MANOVA).

This study is significant because it addresses student mental health using technology-based interventions like online mindfulness applications. As a nursing student, you should consider how such tools could be integrated into university health services or student support programs to improve well-being and reduce the burden of mental health issues among students. The abstract clearly states that Phase I (October 2025 - September 2026) had three objectives: developing the Mind Space application; testing its feasibility for Thai university students; and determining the effect size on mental health outcomes in a pilot study. The primary aim of Phase II is to examine these effects more thoroughly.

The abstract does not provide information about sample sizes, specific preliminary findings from the pilot study (Phase I), or details about whether this will be a randomized controlled trial for Phase II. It also doesn't specify if there are any plans for dissemination beyond ClinicalTrials.gov registration.

Source abstract

Study Overview

Development of the online mindfulness-based intervention (MFU-mindful Application for Thai university students: Phase II

Objectives:

Phase I: (October 2025 to September 2026)

1. To develop the mindfulness-based intervention (Mind Space application) for Thai university students. 2. To test the feasibility of the mindfulness-based intervention (Mind space Application) for Thai university students. 3. To determine the effect size of mindfulness-based intervention (Mind space Application) on mental health outcomes for Thai university students: A pilot study. Phase II: (October 2026 to December 2026)

1\. To examine the effects of mindfulness-base intervention (Mindspace Application) on mental health outcomes for Thai university students For this research project, investigators will develop the mindfulness-based intervention (Mindspace application) based on mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT) by encouraging participants to pay attention to their present thoughts, emotions, feelings, and behaviors without judgment. This attention will help them learn the relationship between their thoughts, emotions, and behaviors and their mental health outcomes (mindfulness, stress, anxiety, and depression), though. mindfulness practice (body scan, sitting meditation, and mindful movement) using an online application). Furthermore, investigators will teach participants how to shape their thoughts and manage their wandering minds and negative and irritable thoughts. Finally, participants will learn how to become an individual with reasonable flexibility and positive thoughts.

Settings: the researchers plan to conduct the program in three universities in Northern Thailand.

Population and sample:

Population: Thai university students who are between years 1 and 4 (undergraduate).

Sample:

Phase I: Mae Fah Luang University, Phayao University, and Utraradit University students who are studying during the Fall semester, year 2026. Investigators will specifically recruit volunteers who:

Inclusion criteria:

1. are current studying in years 1-4 of undergraduate programs 2. can read, speak, and write in Thai 3. be risk of the mental health problem (score higher than 6 on the General Health Questionnaire (GHQ-28) 4. have no history of learning disorders (ADHD, other specific learning disorders) 5. have no psychiatric disorders (schizophrenia, adjustment disorders, delusion disorders, and substance use disorders) 6. have no meditation experience within the past 6 months

Exclusion criteria:

1. have a limitation for mindful movement (hearing loss, blindness, and movement limitations) 2. They may feel uncomfortable or distressed and may not be able to participate in each mindfulness-based intervention session.

Conceptual frameworks. For this research project, the investigators will develop and refine an online mindfulness-based intervention, the Mind Space Application, grounded in the principles of Mindfulness-Based Stress Reduction (MBSR; Kabat-Zinn, 2003) and Mindfulness-Based Cognitive Therapy (MBCT; Segal et al., 2002). The program is designed to cultivate nonjudgmental awareness of thoughts, feelings, emotions, and behaviors among university students (Kabat-Zinn, 2003). In addition, it aims to enhance participants' understanding of the interrelationships among cognitions, emotions, affective experiences, and behaviors that contribute to psychological distress, including stress, anxiety, and depressive symptoms.

The intervention incorporates core mindfulness practices delivered via an online application, including body scan exercises, sitting meditation, and mindfulness-based movement for relaxation. Furthermore, participants will be guided to develop cognitive awareness and adaptive responses to internal and external stressors, with particular emphasis on recognizing and managing automatic thoughts (wandering mind), negative thoughts, and irrational or maladaptive cognitions. Through this process, participants are encouraged to cultivate more rational, flexible, and positive thinking patterns.

The researchers anticipate that this program will enhance mindfulness skills and, in turn, contribute to reductions in stress, anxiety, and depressive symptoms among the study participants.

The effectiveness of the Mind Space application will be examined across both short-term and long-term periods. Short-term effects will be assessed at baseline and immediately post-intervention (8 weeks), while long-term effectiveness will be evaluated at a 6-month follow-up. Outcomes in the intervention group will be compared with those in a control group. The primary outcome variables include mental health indicators-stress, anxiety, and depressive symptoms-as well as levels of mindfulness among Thai university students. Data will be analyzed using a one-way repeated-measures multivariate analysis of variance (MANOVA).

Study type: Clinical trial - NOT_YET_RECRUITING

Evidence appraisal

Main Findings

  • The Mind Space application aims to enhance nonjudgmental awareness of thoughts, emotions, feelings, and behaviors among Thai university students
  • The intervention incorporates mindfulness practices (body scan, sitting meditation, mindful movement) delivered via an online application
  • Participants are guided to develop cognitive awareness and adaptive responses to stressors, focusing on managing automatic, negative, or irrational thoughts
  • The program aims for participants to cultivate more rational, flexible, and positive thinking patterns
  • Effectiveness will be assessed through short-term (8 weeks post-intervention) and long-term (6-month follow-up) outcomes compared to a control group

Practice transfer

Clinical Relevance

  • Online mindfulness applications like Mind Space could offer accessible mental health support for university students in Thailand
  • The structured approach combining MBSR/MBCT principles with digital delivery may be adaptable for other populations or settings facing similar stressors
  • If effective, such interventions could reduce the burden of stress, anxiety, and depressive symptoms among student populations
  • Nurses working in academic or community health settings might consider advocating for or integrating evidence-based mindfulness tools into support programs
  • The study highlights a potential role for technology-assisted mental wellness strategies within broader public health initiatives targeting youth

Faculty notes

Educational Relevance

This article describes 'Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II,' a clinical trial protocol originating from Mae Fah Luang University and registered on ClinicalTrials.gov. The study aims to develop, test feasibility, and assess effect size in a pilot phase (Phase I), followed by examining effects more comprehensively in Phase II.

The core objective of Phase II is 'To examine the effects of mindfulness-base intervention (Mindspace Application) on mental health outcomes for Thai university students.' The Mind Space application is designed based on established principles from Mindfulness-Based Stress Reduction (MBSR; Kabat-Zinn, 2003) and Mindfulness-Based Cognitive Therapy (MBCT; Segal et al., 2002). It encourages participants to cultivate nonjudgmental awareness of their present thoughts, emotions, feelings, and behaviors. This heightened self-awareness is intended to help students understand the interrelationships among cognitions, emotions, affective experiences, and behaviors that contribute to psychological distress (stress, anxiety, depressive symptoms).

The intervention incorporates core mindfulness practices delivered via an online application: body scan exercises, sitting meditation, and mindfulness-based movement for relaxation. Participants will be guided in developing cognitive awareness and adaptive responses to internal and external stressors, with particular emphasis on recognizing and managing automatic thoughts (wandering mind), negative thoughts, and irrational or maladaptive cognitions. The ultimate aim is to encourage participants to cultivate more rational, flexible, and positive thinking patterns.

The study will be conducted in three universities located in Northern Thailand: Mae Fah Luang University, Phayao University, and Utraradit University. The target population consists of Thai university students enrolled in undergraduate programs (years 1-4). For Phase I recruitment during the Fall semester of 2026 at these specific institutions, inclusion criteria were being an undergraduate student in years 1-4; ability to read, speak, and write in Thai; scoring higher than 6 on the General Health Questionnaire (GHQ-28), indicating a risk for mental health problems; no history of learning disorders or psychiatric disorders (schizophrenia, adjustment disorders, delusion disorders, substance use disorders); and having no meditation experience within the past 6 months. Exclusion criteria included limitations for mindful movement (hearing loss, blindness, movement limitations) and being uncomfortable or distressed to participate in each session.

The effectiveness of Mind Space will be examined across both short-term (immediately post-intervention at 8 weeks) and long-term periods (6-month follow-up). Outcomes in the intervention group will be compared with those in a control group. Primary outcome variables include mental health indicators—stress, anxiety, depressive symptoms—and levels of mindfulness among Thai university students. Data analysis will use one-way repeated-measures multivariate analysis of variance (MANOVA).

This study is significant as it addresses student mental health using technology-based interventions like online mindfulness applications. As an instructor or faculty member in nursing education, you might consider how such tools could be integrated into university health services or student support programs to improve well-being and reduce the burden of mental health issues among students. The abstract does not provide information about sample sizes for Phase I or II, nor details on any preliminary findings from the pilot study mentioned in Phase I. It also doesn't specify whether this is a randomized controlled trial design for Phase II.

Critical appraisal

Limitations

  • Abstract does not specify sample sizes for Phase I pilot study or anticipated Phase II trial
  • Details on the control group design (e.g., active vs. passive) are absent from the abstract
  • No information provided about whether this will be a randomized controlled trial in Phase II

Classroom use

Discussion Questions

  • How might cultural factors specific to Thai university students influence their engagement with and perceived benefits of an online mindfulness application?
  • What are the potential barriers (e.g., internet access, digital literacy) for implementing such a program widely across diverse student populations?
  • Beyond stress, anxiety, and depression, what other mental health outcomes or academic performance metrics could be valuable to assess in future iterations of this research?
  • How can findings from Phase II inform decisions about scalability, cost-effectiveness, and long-term sustainability of the Mind Space application as an intervention tool?
  • What ethical considerations are particularly relevant when developing and deploying online mental health interventions for vulnerable populations like university students?
  • Discussion question 6: What does "Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II" help nursing students evaluate?
  • Discussion question 7: What does "Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II" help nursing students evaluate?
  • Discussion question 8: What does "Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II" help nursing students evaluate?
  • Discussion question 9: What does "Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II" help nursing students evaluate?
  • Discussion question 10: What does "Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II" help nursing students evaluate?

Search-ready answers

Frequently asked questions

What is the primary objective of Phase II of this mindfulness-based intervention study?

The primary objective of Phase II is to examine the effects of the mindfulness-base intervention (Mindspace Application) on mental health outcomes for Thai university students.

Which universities are involved in conducting this research program?

The researchers plan to conduct the program in three universities in Northern Thailand: Mae Fah Luang University, Phayao University, and Utraradit University.

What is the target population for recruitment in Phase I of this study?

The target population for recruitment in Phase I consists of Thai university students who are between years 1 and 4 (undergraduate) studying during the Fall semester of year 2026 at Mae Fah Luang University, Phayao University, or Utraradit University.

What specific mental health risk score is used as an inclusion criterion for participants?

A key inclusion criterion is that volunteers must have a General Health Questionnaire (GHQ-28) score higher than 6, indicating a potential risk of mental health problems.

Which mindfulness-based programs form the basis for developing the Mind Space Application?

The Mind Space Application is being developed and refined based on the principles of Mindfulness-Based Stress Reduction (MBSR; Kabat-Zinn, 2003) and Mindfulness-Based Cognitive Therapy (MBCT; Segal et al., 2002).

What are three core mindfulness practices that will be delivered via the online application?

The online application will deliver body scan exercises, sitting meditation, and mindfulness-based movement for relaxation.

How long is the intervention period in Phase II of this study?

Phase II of this research project runs from October 2026 to December 2026.

What are two primary outcome variables that will be measured in this study?

The primary outcome variables include mental health indicators such as stress, anxiety, and depressive symptoms, as well as levels of mindfulness among Thai university students.

Which statistical method is planned for analyzing the data from this clinical trial?

Data will be analyzed using a one-way repeated-measures multivariate analysis of variance (MANOVA).

What are two examples of exclusion criteria mentioned in the study description?

Two examples of exclusion criteria include: 1. having limitations for mindful movement such as hearing loss, blindness, or movement limitations; and 2. feeling uncomfortable or distressed to participate in each mindfulness-based intervention session.