Nursing research summary

Preventive Effects of Light Music on Postpartum Anxiety and Depression in Primiparous Women

In a retrospective study of 120 first-time mothers, adding twice-daily light music sessions to standard postpartum care was associated with lower depression, anxiety, and stress-hormone levels, better sleep, higher exclusive breastfeeding rates, and higher quality-of-life scores at six weeks compared to standard care alone. The non-randomized, single-site design means these findings are promising but preliminary.

Noise and Health Published 2025 4 min read DOI 10.4103/nah.nah_56_25

In brief

In a retrospective study of 120 first-time mothers, adding twice-daily light music sessions to standard postpartum care was associated with lower depression, anxiety, and stress-hormone levels, better sleep, higher exclusive breastfeeding rates, and higher quality-of-life scores at six weeks compared to standard care..

What this article is about

Quick Answer

In a retrospective study of 120 first-time mothers, adding twice-daily light music sessions to standard postpartum care was associated with lower depression, anxiety, and stress-hormone levels, better sleep, higher exclusive breastfeeding rates, and higher quality-of-life scores at six weeks compared to standard care alone. The non-randomized, single-site design means these findings are promising but preliminary.

Student takeaways

Key Takeaways

  • At six weeks postpartum, the music therapy group had significantly lower Edinburgh Postnatal Depression Scale (EPDS) and Perinatal Anxiety Screening Scale (PASS) scores than the standard care group (both P<0.001), while standard care scores had risen slightly over the same period.
  • Sleep quality, measured by the Pittsburgh Sleep Quality Index, improved more in the music therapy group across all seven component domains by six weeks (total score P<0.001).
  • Salivary cortisol and salivary alpha-amylase, both physiological stress biomarkers, decreased significantly more in the music therapy group than the standard care group by six weeks (both P<0.001).
  • Exclusive breastfeeding at six weeks postpartum was reported in 79.03% of the music therapy group compared with 53.45% of the standard care group (P=0.003).
  • All four WHOQOL-BREF quality-of-life domains (physical health, psychological well-being, social relationships, environment) were significantly higher in the music therapy group at six weeks (P<0.05 for all domains).

Student summary

Why This Research Matters

Postpartum anxiety and depression are common problems after childbirth. In Canada, a national survey of recent mothers found that about 18% reported symptoms consistent with postpartum depression and about 14% symptoms consistent with a postpartum anxiety disorder (nearly a quarter reported either), and many cases go undetected without formal screening. Medications exist, but they raise concerns about safety during breastfeeding, so researchers keep looking for non-drug options nurses can offer at the bedside. This retrospective study from a hospital in China, published in the journal Noise and Health, asked whether a structured program of "light music" (soft instrumental listening) could help prevent postpartum anxiety and depression in first-time mothers.

The researchers reviewed records for 120 primiparous (first-time) mothers treated between June 2022 and June 2024. Fifty-eight women had received standard postnatal nursing care alone, while 62 women had received the same standard care plus a structured light music program. The music intervention began within 24 hours of birth: twice-daily 30-minute sessions combined five minutes of guided breathing with soft instrumental tracks played through noise-canceling headphones at a gentle volume. After discharge, participants borrowed an audio player loaded with the same music library and received brief weekly telephone counselling, with app-based tracking of how often they used it.

At three days postpartum, the two groups looked similar on every measure. By six weeks postpartum, the music group showed meaningfully lower depression scores (Edinburgh Postnatal Depression Scale) and lower anxiety scores (Perinatal Anxiety Screening Scale) than the standard care group, whose scores had actually risen slightly over the same period. Sleep quality, measured with the Pittsburgh Sleep Quality Index, was also better in the music group across all its component domains. When the researchers looked at the proportion of women who anxiety screening flagged as clinically significant at six weeks, the music group had a much lower rate (about 6% versus about 21%); depression screening rates were lower too, though that particular difference did not reach statistical significance.

The study also measured physiological stress directly using saliva samples. Both cortisol (a stress hormone) and salivary alpha-amylase (a marker of sympathetic nervous system activity) dropped further in the music group than in the standard care group by six weeks. This matters because it links a subjective feeling of "less anxious" to an objective biological signal of reduced stress-system activation, strengthening the case that something physiological, not just a placebo effect, was happening.

Two additional outcomes stood out. Exclusive breastfeeding at six weeks was reported by about 79% of the music group compared with about 53% of the standard care group. And scores on the WHOQOL-BREF quality-of-life questionnaire were higher in the music group across all four domains it measures: physical health, psychological well-being, social relationships, and environment.

The authors propose several possible mechanisms: soft music may promote dopamine and serotonin activity linked to mood regulation, shift the balance of the autonomic nervous system toward calming (parasympathetic) activity, and improve sleep, which itself is closely tied to mood. Better sleep and lower stress hormones may also support the physiological reflexes involved in milk letdown, which could partly explain the breastfeeding difference.

As a nursing student, this study is a useful example of how a low-cost, low-risk nursing intervention can be layered onto standard postpartum care without displacing medical care. But it is important to read the results cautiously. This was a retrospective study, meaning nurses did not randomly assign women to groups; women (or their care team) essentially selected which pathway they followed, which opens the door to selection bias. It came from a single hospital in one country, so the specific music library, cultural music preferences, and care setting may not transfer directly to a Canadian unit. Adherence to home listening was tracked by self-report through an app, which is less reliable than an objective measure. Still, the consistency of the findings across psychological, physiological, and functional measures makes light music a plausible, low-risk complementary strategy worth further controlled study before being adopted as routine practice.

Source abstract

Study Overview

Objective: This paper aims to evaluate the preventive effects of light music on postpartum anxiety and depression in primiparous women. Methods: This retrospective study analyzed 120 primiparous women admitted to our hospital from June 2022 to June 2024. Participants were divided into two groups based on the postpartum nursing methods they received: those who received standard care (standard care group: n = 58) and those who received light music therapy (music therapy group: n = 62). Outcomes included Edinburgh Postnatal Depression Scale (EPDS), Perinatal Anxiety Screening Scale (PASS), Pittsburgh Sleep Quality Index (PSQI), salivary cortisol, salivary alpha-amylase (sAA), exclusive breastfeeding (EBF) rates, and World Health Organization Quality of Life Brief Version (WHOQOL-BREF) scale scores at 3-day and 6-week postpartum. Results: At 6 weeks postpartum, the music therapy group showed significantly lower scores of EPDS, PASS, and PSQI compared to the standard care group (P < 0.05). Salivary cortisol and sAA levels were also significantly reduced (P < 0.05). Additionally, the music therapy group exhibited higher EBF rates (79.03% vs. 53.45%, P < 0.05) and significantly improved scores across all domains of WHOQOL-BREF (P < 0.05). Conclusion Light music therapy significantly alleviates postpartum psychological distress, reduces physiological stress, and improves breastfeeding rate and quality of life, which supports its clinical adoption.

Study type: Open access journal article

Evidence appraisal

Main Findings

  • At six weeks postpartum, the music therapy group had significantly lower Edinburgh Postnatal Depression Scale (EPDS) and Perinatal Anxiety Screening Scale (PASS) scores than the standard care group (both P<0.001), while standard care scores had risen slightly over the same period.
  • Sleep quality, measured by the Pittsburgh Sleep Quality Index, improved more in the music therapy group across all seven component domains by six weeks (total score P<0.001).
  • Salivary cortisol and salivary alpha-amylase, both physiological stress biomarkers, decreased significantly more in the music therapy group than the standard care group by six weeks (both P<0.001).
  • Exclusive breastfeeding at six weeks postpartum was reported in 79.03% of the music therapy group compared with 53.45% of the standard care group (P=0.003).
  • All four WHOQOL-BREF quality-of-life domains (physical health, psychological well-being, social relationships, environment) were significantly higher in the music therapy group at six weeks (P<0.05 for all domains).

Practice transfer

Clinical Relevance

  • Structured light music sessions combined with brief guided breathing, started within 24 hours postpartum, may be a low-cost, low-risk adjunct nurses can layer onto standard postpartum care rather than a replacement for it.
  • Because salivary cortisol and alpha-amylase both dropped further in the music group, the intervention may work partly through physiological stress-axis modulation, which nurses could discuss with patients as a rationale for engagement, not just a comfort measure.
  • The association with higher exclusive breastfeeding rates suggests postpartum stress-reduction interventions could be considered as part of broader lactation support strategies, though this link needs confirmation in controlled trials before being promoted as a breastfeeding intervention per se.
  • Given the retrospective, single-site design, nurses and educators should treat these findings as hypothesis-generating rather than as a basis for immediate practice change or replacing validated depression/anxiety screening and referral pathways.
  • Any local adoption of a similar music protocol should preserve validated screening (e.g., EPDS at recommended intervals) alongside the intervention, since music therapy was studied as an adjunct to, not substitute for, standard psychosocial assessment.

Faculty notes

Educational Relevance

This retrospective cohort study (Cai & Wang, Noise and Health, 2025) examined whether a structured light music program, added to standard postpartum nursing care, could reduce postpartum anxiety and depression symptoms in primiparous women. The sample (n=120, drawn from 153 initially screened) was split into a standard care group (n=58) and a music therapy group (n=62) treated at a single Chinese hospital between June 2022 and June 2024. Power analysis indicated a minimum of 52 participants per arm, which the final sample exceeded.

Inclusion criteria required singleton pregnancies at 37+ weeks, complete records, no pre-existing psychiatric diagnosis, and normal hearing; exclusions included multiple gestation, concurrent psychotropic treatment, severe obstetric or neonatal complications, and poor intervention adherence. The music intervention was well-specified for a nursing pedagogy discussion: it used a curated 32-track instrumental library (mean length 4.2 minutes), began within 24 hours postpartum, ran as twice-daily 30-minute sessions (5 minutes of guided breathing plus music) via noise-canceling headphones at 40-45 dB, and continued post-discharge via a loaned device plus weekly 15-20 minute telephone/online counselling, with adherence tracked through a mobile app. Standard care kept ambient noise below 55 dB and included brief daily check-ins without emotional counselling, plus similar weekly post-discharge phone contact — a design choice worth discussing, since it controls for "attention" to some degree while isolating the music/breathing component as the differentiating variable.

At three days postpartum the groups were equivalent on the Edinburgh Postnatal Depression Scale (EPDS), Perinatal Anxiety Screening Scale (PASS), and Pittsburgh Sleep Quality Index (PSQI). By six weeks, the music group showed significantly lower EPDS and PASS scores than standard care (both P<0.001), while the standard care group's scores had risen modestly over the same interval. PSQI total and all seven component scores favored the music group (P<0.05, total P<0.001). Clinically significant anxiety (PASS>21) was lower in the music group (6.45% vs 20.69%, P=0.022); the corresponding depression threshold comparison (EPDS>13: 4.84% vs 12.07%) was not statistically significant, a useful point for discussing the difference between continuous-score effects and dichotomized clinical-threshold effects. Salivary cortisol and alpha-amylase both declined further in the music group by six weeks (both P<0.001), supporting a physiological/HPA-axis-mediated pathway rather than a purely subjective effect. Exclusive breastfeeding at six weeks was higher in the music group (79.03% vs 53.45%, P=0.003), and all four WHOQOL-BREF domains (physical, psychological, social, environmental) favored the music group (P<0.05).

For classroom discussion, the retrospective, non-randomized design is the central appraisal point: allocation to group was not controlled by the researchers, so baseline motivation, socioeconomic factors, or unmeasured confounders (partner support, infant temperament, home environment, external music exposure) could plausibly explain part of the effect. The single-center, single-culture sample limits generalizability to Canadian or other Western postpartum units, where music preference, care models, and ambient hospital noise standards differ. Post-discharge adherence relied on self-report via app rather than objective tracking. The fixed, pre-selected music library may not match individual patient preference, a modifiable design limitation the authors themselves note.

Instructionally, this article works well for teaching students to distinguish observational associational designs from RCTs, to interpret converging biopsychosocial outcome measures (self-report scale, physiological biomarker, and functional/behavioral outcome) as a strength even in a lower-evidence design, and to practice appraisal language around confounding and selection bias before considering practice change. It also offers a concrete, protocol-level example (session timing, duration, volume, headphone use) that could inform a future pilot or quality-improvement proposal in a Canadian postpartum unit, provided it is framed as hypothesis-generating rather than practice-changing evidence.

Critical appraisal

Limitations

  • The retrospective, non-randomized design means group allocation was not controlled by the researchers, introducing potential selection bias between the standard care and music therapy groups.
  • The study was conducted at a single hospital in one country and culture, which limits generalizability of the specific music library, protocol, and effect sizes to other healthcare settings, including Canadian postpartum units.
  • Post-discharge adherence to home music listening was tracked through self-reported mobile app use, which is a less reliable adherence measure than objective monitoring.

Classroom use

Discussion Questions

  • Why is the retrospective, non-randomized design of this study an important limitation when interpreting the reported differences between groups?
  • What are the possible confounding variables that could explain some of the observed differences in EPDS and PASS scores between the standard care and music therapy groups?
  • How does the inclusion of a physiological biomarker (salivary cortisol and alpha-amylase) strengthen or not strengthen the interpretation of the psychological outcome measures?
  • Why might depression screening rates (EPDS>13) not reach statistical significance between groups even though continuous EPDS scores did differ significantly?
  • What role might improved sleep quality play as a mediating pathway between the music intervention and reduced anxiety/depression scores?
  • How might nurses in a Canadian postpartum unit adapt this protocol (timing, duration, volume, headphone use) while accounting for differences in hospital resources and patient population?
  • What ethical or practical considerations arise from using a fixed, pre-selected music library rather than patient-preferred music?
  • How should the association between the music intervention and exclusive breastfeeding rates be interpreted, given the study did not isolate a specific causal mechanism for this outcome?
  • What further research design (e.g., randomized controlled trial, multicenter, longer follow-up) would be needed before this intervention could be recommended as standard postpartum practice?
  • How could a nurse educator use this study to teach students the difference between statistically significant clinical scale differences and clinically meaningful differences in patient care?

Knowledge check

Quiz

1. What type of study design was used to evaluate light music therapy in this article?

  1. Randomized controlled trial
  2. Retrospective cohort study
  3. Systematic review
  4. Case-control study
Answer: Retrospective cohort study
Rationale: The full text describes this as a retrospective cohort analysis examining 120 first-time mothers, with group allocation based on the postpartum nursing methods they had already received, not random assignment.

2. How many primiparous women were in the standard care group versus the music therapy group?

  1. 58 standard care vs. 62 music therapy
  2. 62 standard care vs. 58 music therapy
  3. 60 standard care vs. 60 music therapy
  4. 50 standard care vs. 70 music therapy
Answer: 58 standard care vs. 62 music therapy
Rationale: The abstract states participants were divided into 'standard care group: n = 58' and 'music therapy group: n = 62', totaling 120 women.

3. At six weeks postpartum, how did EPDS and PASS scores compare between groups?

  1. Both scores were significantly lower in the music therapy group compared to standard care
  2. Both scores were significantly lower in the standard care group
  3. There was no significant difference between groups on either scale
  4. EPDS was lower in music therapy but PASS was lower in standard care
Answer: Both scores were significantly lower in the music therapy group compared to standard care
Rationale: The full text reports EPDS (7.79 to 6.45 in the music group vs 7.82 to 8.23 in standard care) and PASS scores were both significantly lower in the music therapy group at six weeks (P<0.001 for both).

4. What two physiological (biochemical) stress markers were measured in this study?

  1. Salivary cortisol and salivary alpha-amylase
  2. Blood pressure and heart rate variability
  3. Serum cortisol and blood glucose
  4. C-reactive protein and white blood cell count
Answer: Salivary cortisol and salivary alpha-amylase
Rationale: The abstract and full text specify that salivary cortisol and salivary alpha-amylase (sAA) were measured as physiological stress markers, both of which decreased more in the music therapy group by six weeks.

5. What was the exclusive breastfeeding (EBF) rate at 6 weeks in the music therapy group compared to standard care?

  1. 79.03% vs. 53.45%
  2. 53.45% vs. 79.03%
  3. 65% vs. 65%
  4. 90% vs. 60%
Answer: 79.03% vs. 53.45%
Rationale: The abstract states the music therapy group 'exhibited higher EBF rates (79.03% vs. 53.45%, P < 0.05)' compared to the standard care group.

6. When did the two groups differ from each other on the measured outcomes?

  1. The groups were similar at 3 days but differed significantly by 6 weeks postpartum
  2. The groups differed significantly at 3 days but became similar by 6 weeks
  3. The groups differed at both time points equally
  4. No timepoint comparison was made in the study
Answer: The groups were similar at 3 days but differed significantly by 6 weeks postpartum
Rationale: The full text notes that at three days postpartum the two groups looked similar on every measure, with significant differences emerging by the six-week assessment.

7. Which of the following is an author-stated limitation of this study?

  1. The retrospective design introduces selection bias because group allocation was not randomized
  2. The sample size was too small to reach statistical power
  3. The study included men as well as women
  4. The music therapy sessions lasted too long to be practical
Answer: The retrospective design introduces selection bias because group allocation was not randomized
Rationale: The full text explicitly lists 'retrospective design introduces selection bias (non-randomized group allocation)' as an author-stated limitation.

8. According to the WHOQOL-BREF results, how many quality-of-life domains showed significant improvement in the music therapy group?

  1. All four domains (physical, psychological, social, environmental)
  2. Only the physical health domain
  3. Only psychological and social domains
  4. None reached statistical significance
Answer: All four domains (physical, psychological, social, environmental)
Rationale: The abstract states the music therapy group 'exhibited... significantly improved scores across all domains of WHOQOL-BREF (P < 0.05)', and the full text confirms all four domains improved.

9. What clinical concern about pharmacological (medication-based) treatment for postpartum depression/anxiety is raised as rationale for exploring non-drug interventions like music therapy?

  1. Concerns about medication safety during breastfeeding/lactation
  2. Medications are too expensive for most patients
  3. No medications have ever been tested for postpartum depression
  4. Medications work faster than needed
Answer: Concerns about medication safety during breastfeeding/lactation
Rationale: The full text introduction notes that pharmacological options are limited and raise 'lactation safety concerns,' motivating the search for non-pharmacological alternatives such as music therapy.

10. What follow-up research do the study authors recommend before this intervention could be broadly adopted?

  1. Multicenter randomized controlled trials with longer follow-up and objective adherence monitoring
  2. No further research is needed since the findings are conclusive
  3. Only qualitative interviews with mothers
  4. Animal studies to confirm the neurobiological mechanism
Answer: Multicenter randomized controlled trials with longer follow-up and objective adherence monitoring
Rationale: The full text states the authors 'recommend future multicenter randomized controlled trials with extended 6-12 month follow-up, objective adherence monitoring... personalized music delivery algorithms, and neuroimaging investigations.'

Study cards

Flashcards

What was the main objective of this study?

To evaluate the preventive effects of light music therapy on postpartum anxiety and depression in primiparous (first-time) mothers.

What type of study design was used?

A retrospective cohort study comparing primiparous women who received standard care versus standard care plus light music therapy.

How many total participants were included, and how were they split?

120 primiparous women: 58 in the standard care group and 62 in the music therapy group.

When did the music therapy intervention begin relative to birth?

Within 24 hours postpartum.

How often and how long were the in-hospital music sessions?

Twice daily, 30 minutes each session, including 5 minutes of guided breathing followed by music listening.

At what volume and equipment was the music delivered?

40-45 dB through noise-canceling headphones.

What happened after hospital discharge in the music therapy group?

Participants used a loaned audio device with the same music library and received weekly 15-20 minute online stress management counselling, with adherence tracked via a mobile app.

What scale was used to measure postpartum depression symptoms?

The Edinburgh Postnatal Depression Scale (EPDS).

What scale was used to measure postpartum anxiety symptoms?

The Perinatal Anxiety Screening Scale (PASS).

What scale was used to assess sleep quality?

The Pittsburgh Sleep Quality Index (PSQI).

What two salivary biomarkers were used to measure physiological stress?

Salivary cortisol and salivary alpha-amylase (sAA).

At what two timepoints were outcomes assessed?

3 days postpartum and 6 weeks postpartum.

Were the two groups different at the 3-day assessment?

No, the groups were similar on all measures at 3 days postpartum; differences emerged by 6 weeks.

What happened to EPDS and PASS scores in the standard care group between 3 days and 6 weeks?

Scores rose slightly (worsened), while the music therapy group's scores declined (improved) over the same period.

What was the exclusive breastfeeding rate difference at 6 weeks?

79.03% in the music therapy group versus 53.45% in the standard care group.

What tool was used to assess quality of life, and how many domains does it measure?

The WHOQOL-BREF (World Health Organization Quality of Life Brief Version), which measures four domains: physical health, psychological well-being, social relationships, and environment.

Name one proposed biological mechanism for the music intervention's effect.

Music may modulate the HPA (stress) axis and shift autonomic balance toward parasympathetic (calming) activity, reducing cortisol and alpha-amylase.

What is the primary limitation related to how participants were assigned to groups?

The study was retrospective and non-randomized, so group allocation was not controlled, introducing potential selection bias.

Why is the single-center, single-country setting a limitation?

It limits how well the findings, music library, and protocol generalize to other healthcare systems and cultures, such as Canadian postpartum units.

What did the researchers recommend for future study of this intervention?

Multicenter randomized controlled trials with longer (6-12 month) follow-up, objective adherence monitoring, personalized music delivery, and neuroimaging studies of mechanisms.

Search-ready answers

Frequently asked questions

What is light music therapy for postpartum women?

In this study, light music therapy was a structured program of soft instrumental music (32 tracks averaging about 4 minutes each) delivered via headphones in twice-daily 30-minute sessions combined with guided breathing, starting within 24 hours of birth and continuing after discharge.

Does music therapy help prevent postpartum depression?

In this single-hospital retrospective study of 120 first-time mothers, women who received structured light music therapy alongside standard care had significantly lower depression (EPDS) scores at six weeks postpartum than those who received standard care alone, though this was an observational, non-randomized comparison.

Can music reduce postpartum anxiety?

Yes, in this study anxiety scores (PASS) at six weeks were significantly lower in the music therapy group, and the proportion with clinically significant anxiety was lower (6.45% vs 20.69%) compared to standard care.

How does music therapy affect stress hormones after childbirth?

The study found that salivary cortisol and salivary alpha-amylase, two physiological stress markers, decreased more in the music therapy group than the standard care group by six weeks postpartum, suggesting a biological stress-reduction effect.

Is there a link between music therapy and breastfeeding success?

The study found an association: 79.03% of the music therapy group reported exclusive breastfeeding at six weeks compared with 53.45% of the standard care group, though the study did not isolate the exact mechanism behind this link.

What are the limitations of this music therapy study?

It was a retrospective, non-randomized, single-hospital study with self-reported adherence tracking and a fixed music library, so the findings should be considered preliminary rather than definitive evidence for practice change.

How is postpartum anxiety and depression usually treated?

The study notes pharmacological options like estradiol and brexanolone have shown some effectiveness but raise lactation safety concerns, which is part of the rationale for exploring safer non-drug approaches like music therapy.

How long did the light music sessions last in the study?

Each hospital session was 30 minutes (5 minutes of guided breathing plus music), delivered twice daily, with post-discharge home listening supported by a loaned audio device.

What scales are used to screen for postpartum depression and anxiety?

This study used the Edinburgh Postnatal Depression Scale (EPDS) for depression and the Perinatal Anxiety Screening Scale (PASS) for anxiety; the EPDS is widely used in Canadian postpartum screening as well.

Should hospitals adopt light music therapy programs based on this study?

Not yet as a standalone practice change: because the study was retrospective and conducted at a single site, the authors and this appraisal recommend randomized, multicenter trials before broader clinical adoption.